Vascular area with marked resistance elevation in one-clip, two-kidney renovascular hypertensive rats.
نویسندگان
چکیده
منابع مشابه
Cardiac output in conscious one-clip, two-kidney renovascular hypertensive rats.
Cardiac output and arterial pressure in the conscious state were observed in one-clip, two-kidney renovascular hypertensive rats with a chronically implanted electromagnetic flow probe and an arterial cannula. Normal Wistar rats were used as controls. At rest, cardiac output per body weight did not show any difference between hypertensive rats and normal controls. This kind of experimental hype...
متن کاملImpaired renorenal reflexes in two-kidney, one clip hypertensive rats.
In normotensive rats, stimulation of renal mechanoreceptors by an increase in ureteral pressure results in a contralateral inhibitory renorenal reflex response with contralateral natriuresis. Similar effects are produced by stimulation of renal chemoreceptors by renal pelvic perfusion with 0.9 M NaCl. However, in spontaneously hypertensive rats the renorenal reflex responses to renal mechanorec...
متن کاملTwo-kidney, two clip renovascular hypertensive rats can be used as stroke-prone rats.
BACKGROUND AND PURPOSE The cerebrovascular lesions in stroke-prone spontaneously hypertensive rats are not only dependent on high blood pressure but partly related to pressure-independent genetic factors. The aim of the present study was to observe whether spontaneous stroke occurred in renovascular hypertensive rats without a genetic deficiency. METHODS The 1-kidney, 1 clip (1k1c); 2-kidney,...
متن کاملVascular renin-angiotensin system in two-kidney, one clip hypertensive rats.
The possible role of the renin-angiotensin system in the maintenance of hypertension in two-kidney, one clip hypertensive rats was studied. Plasma renin activity rose rapidly and markedly in association with the elevation of blood pressure and then decreased gradually, although blood pressure remained high. Renin activity in the lung, aorta, and mesenteric artery also increased with the develop...
متن کاملEffect of clonidine on blood pressure in chronic one-kidney, one-clip and two-kidney, one-clip hypertensive rats.
Oral administration of clonidine lowered the high blood pressure in two-kidney, one-clip hypertensive rats in chronic stage (three to four months), but not in one-kidney, one-clip hypertensive rats. This reduction of blood pressure was well correlated with decrease in plasma renin concentration, but not with decrease in urinary noradrenaline excretion. These results suggest that the reduction o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Japanese Journal of Physiology
سال: 1985
ISSN: 1881-1396,0021-521X
DOI: 10.2170/jjphysiol.35.139